Thomas J Schnitzer Selected Research

Naproxen (Naprosyn)

1/2022	Validating a biosignature-predicting placebo pill response in chronic pain in the settings of a randomized controlled trial.
12/2021	Sex-Specific Pharmacotherapy for Back Pain: A Proof-of-Concept Randomized Trial.
2/2011	Efficacy and safety of naproxcinod in patients with osteoarthritis of the knee: a 53-week prospective randomized multicenter study.
9/2009	Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis.
12/2005	Comparison of the COX-inhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of Osteoarthritis of the knee.
8/2005	Need for common internal controls when assessing the relative efficacy of pharmacologic agents using a meta-analytic approach: case study of cyclooxygenase 2-selective inhibitors for the treatment of osteoarthritis.
8/2004	Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial.
8/2004	Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial.
2/2003	Serious lower gastrointestinal clinical events with nonselective NSAID or coxib use.

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Thomas J Schnitzer Research Topics

Disease

39	Pain (Aches) 01/2022 - 01/2002
32	Osteoarthritis 01/2022 - 01/2002
15	Knee Osteoarthritis 01/2022 - 01/2002
9	Spinal Cord Injuries (Spinal Cord Injury) 01/2022 - 11/2010
8	Back Pain (Backache) 01/2022 - 10/2008
8	Chronic Pain 12/2021 - 01/2005
6	Hip Osteoarthritis (Coxarthrosis) 01/2022 - 06/2009
6	Arthritis (Polyarthritis) 01/2009 - 01/2002
5	Low Back Pain (Lumbago) 01/2022 - 10/2008
5	Rheumatoid Arthritis 01/2009 - 01/2002
4	Arthralgia (Joint Pain) 01/2020 - 07/2005
4	Hypertension (High Blood Pressure) 04/2016 - 06/2005
4	Osteoporosis 08/2009 - 05/2002
3	Hemorrhage 09/2016 - 02/2003
2	Paresthesia (Dysesthesia) 01/2022 - 10/2010
2	Musculoskeletal Pain 01/2020 - 01/2006
2	Wounds and Injuries (Trauma) 01/2020 - 08/2003
2	Stroke (Strokes) 04/2016 - 03/2007
2	Coronary Artery Disease (Coronary Atherosclerosis) 04/2016 - 11/2010
2	Ulcer 08/2004 - 01/2002
1	Bradycardia 01/2022
1	Hypesthesia (Numbness) 01/2022
1	Orthostatic Hypotension (Postural Hypotension) 01/2022
1	Kidney Calculi (Kidney Stone) 01/2020
1	Pharyngitis (Sore Throat) 01/2020
1	Avulsion Fractures 01/2020
1	Abdominal Pain (Pain, Abdominal) 01/2020
1	Neck Pain (Cervicalgia) 01/2020
1	Contusions 01/2020
1	Joint Diseases (Joint Disease) 11/2019
1	Metabolic Bone Diseases (Osteopenia) 10/2019
1	Neutropenia 01/2019
1	Synovitis 01/2019
1	Injection Site Reaction 01/2019
1	Acute Coronary Syndrome 09/2016
1	Cardiovascular Diseases (Cardiovascular Disease) 04/2016
1	Peripheral Arterial Disease 04/2016
1	Hyperlipidemias (Hyperlipidemia) 04/2016
1	Diarrhea 11/2010
1	Brain Injuries (Brain Injury) 11/2010
1	Headache (Headaches) 10/2010
1	Respiratory Tract Infections (Respiratory Tract Infection) 10/2010

Drug/Important Bio-Agent (IBA)

10	tanezumabIBA 01/2022 - 10/2010
9	Naproxen (Naprosyn)FDA LinkGeneric 01/2022 - 02/2003
9	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2021 - 01/2002
9	Analgesics (Analgesic Drugs)IBA 01/2021 - 01/2006
8	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2006 - 01/2002
7	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2009 - 01/2002
6	Pharmaceutical PreparationsIBA 01/2022 - 12/2004
6	Celecoxib (Celebrex)FDA Link 11/2011 - 01/2002
6	rofecoxib (Vioxx)FDA Link 07/2006 - 01/2002
5	Prostaglandins AIBA 01/2022 - 06/2015
5	lumiracoxib (prexige)IBA 11/2011 - 08/2004
5	naproxen-n-butyl nitrateIBA 05/2011 - 12/2005
4	Opioid Analgesics (Opioids)IBA 06/2021 - 01/2006
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 04/2016 - 08/2004
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2011 - 12/2005
4	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2006 - 01/2002
3	Zoledronic Acid (Zometa)FDA Link 01/2022 - 01/2016
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
3	Nerve Growth Factor (NGF)IBA 11/2019 - 10/2010
3	Teriparatide (Parathar)FDA Link 10/2019 - 08/2013
3	Vitamin D FDA LinkGeneric 11/2010 - 08/2003
3	Ibuprofen (Motrin)FDA LinkGeneric 01/2005 - 08/2004
2	Alendronate (Alendronate Sodium)FDA LinkGeneric 10/2019 - 05/2002
2	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 09/2016 - 04/2016
2	Omeprazole (Prilosec)FDA LinkGeneric 09/2016 - 11/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2014 - 02/2003
2	Parathyroid Hormone (Parathormone)IBA 08/2013 - 03/2007
2	CalciumIBA 03/2007 - 08/2003
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2006 - 01/2002
1	levodopa drug combination carbidopa (Nakom)FDA LinkGeneric 12/2021
1	ElementsIBA 02/2021
1	Hormones (Hormone)IBA 01/2021
1	4-hexyloxyaniline (HOA)IBA 01/2020
1	Monoclonal AntibodiesIBA 11/2019
1	fasinumabIBA 11/2019
1	Interleukin-1 (Interleukin 1)IBA 01/2019
1	InterleukinsIBA 01/2019
1	lutikizumabIBA 01/2019
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 01/2018
1	Cycloserine (Seromycin)FDA Link 01/2016
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2016
1	ViscosupplementsIBA 07/2014
1	SteroidsIBA 07/2014
1	MineralsIBA 06/2013
1	zucapsaicinIBA 03/2012
1	EtoricoxibIBA 01/2012
1	Cyclooxygenase InhibitorsIBA 05/2011
1	Clopidogrel (Plavix)FDA Link 11/2010
1	25-hydroxyvitamin DIBA 11/2010

Therapy/Procedure

16	Therapeutics 01/2021 - 01/2002
7	Analgesia 01/2022 - 01/2005
2	Treatment Delay 01/2022 - 11/2021
2	Percutaneous Coronary Intervention 09/2016 - 04/2016
2	Pain Management 11/2013 - 01/2006
1	Drug Therapy (Chemotherapy) 12/2021
1	Replacement Arthroplasty 01/2019
1	Injections 07/2014
1	Conservative Treatment 07/2014